Monday, January 31, 2011

Cancer

Cancer (medical term: malignant neoplasm ) is a class of disease which a group of cells display uncontrolled growth, invasion that intrudes upon and destroys adjacent tissues, and sometimes metastasis , or spreading to other locations in the body via lymph or blood. These three malignant properties of cancers differentiate them from benign tumors, which do not invade or metastasize.

Researchers divide the causes of cancer into two groups: those with a hereditary genetic cause and those an environmental cause. Environmental in this sense means all non-hereditary factors, and encompasses far more than environmental pollusion. About 5-10% of cancers are directly due to hereditary genetic factors. The remaining 90-95% of cases are due to environmental factors, such as old age, lifestyle choices, tobacco use, dietary choices, obesity, infections, radiation, lack of physical activity, and environmental pollutants. These environmental factors cause or enhance non-hereditary abnormalities in the genetic material of cells. Cell reproduction is an extremely complex process that is normally tightly regulated by several classes of genes, including oncogenes and tumer suppressor genes . Hereditary or acquired abnormalities in these regulatory genes can lead to the development of cancer.

The presence of cancer can be suspected on the basis of symptoms, or findings on radiology. Definitive diagnosis of cancer, however, requires the microscopic examination of a biopsy specimen. Most cancers can be treated. Possible treatments include chemotherapy, radiotherapy and surgery . The prognosis is influenced by the type of cancer and the extent of disease. While cancer can affect people of all ages, and a few types of cancer are more common in children, the overall risk of developing cancer increases with age. In 2007 cancer caused about 13% of all human deaths worldwide (7.9 million), and the number of cases is rising as more people live to old age.


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